Publications

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Patents

Anti-LRRC15 Antibodies and Antibody-Drug Conjugates (ADCs)

Published in World Intellectual Property Organization (WIPO), 2026

Two related patent publications detailing isolated anti-LRRC15 antibodies and specific antibody-drug conjugates (ADCs) for the treatment of cancer.

Recommended citation: Bristol Myers Squibb (Co-inventor: Yuntao Zhang). (2026). "Anti-LRRC15 Antibodies and Antibody-Drug Conjugates." WIPO Patent Publication Nos. WO/2026/112469 and WO/2026/112472.
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Journal Articles

Chirality Effects on the Intrinsic Acidity of Isomeric Tripeptides Containing a D/L-Cysteine on the N-terminus: CAA and dCAA

Published in International Journal of Mass Spectrometry, Volume 514, August 2025, 117472, 2025

This paper investigates the chirality effects on the intrinsic acidity of isomeric tripeptides containing a D/L-Cysteine on the N-terminus.

Recommended citation: Shiyuan Wang, Zachary Buen, Kimberlyann R. Harvey, Yuntao Zhang, Jianhua Ren. (2025). "Chirality effects on the intrinsic acidity of isomeric tripeptides containing a D/L-Cysteine on the N-terminus: CAA and dCAA." International Journal of Mass Spectrometry, 514, 117472. https://doi.org/10.1016/j.ijms.2025.117472
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Subtle chirality effects of a D/l-Cysteine on the intrinsic acidity and conformation of isomeric tripeptides ACA and AdCA

Published in International Journal of Mass Spectrometry, Volume 469, November 2021, 116685, 2021

This paper investigates the subtle chirality effects of a D/l-Cysteine on the intrinsic acidity and conformation of isomeric tripeptides ACA and AdCA.

Recommended citation: Yuntao Zhang, Zachary Buen, Michael D. Browne, Yadwinder S. Mann, Jianhua Ren. (2021). "Subtle chirality effects of a D/l-Cysteine on the intrinsic acidity and conformation of isomeric tripeptides ACA and AdCA." International Journal of Mass Spectrometry, 469, 116685. https://doi.org/10.1016/j.ijms.2021.116685
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Mass spectrometry studies of the fragmentation patterns and mechanisms of protonated peptoids

Published in Biopolymers, 111(7):e23358, 2020, 2020

This study uses tandem mass spectrometry to characterize the fragmentation patterns and mechanisms of singly and doubly protonated peptoids with basic residues at different positions.

Recommended citation: Jianhua Ren, Yuan Tian, Ekram Hossain, Joshua S Ho, Yadwinder S Mann, Yuntao Zhang, Michael D Browne, Michael D Connolly, Ronald N Zuckermann. (2020). "Mass spectrometry studies of the fragmentation patterns and mechanisms of protonated peptoids." Biopolymers, 111(7):e23358. https://doi.org/10.1002/bip.23358
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Characterization of protonated AcAlaDab and AcDabAla by IRMPD spectroscopy and molecular modeling

Published in International Journal of Mass Spectrometry, Volume 444, October 2019, 116178, 2019

This paper characterizes protonated AcAlaDab and AcDabAla using IRMPD spectroscopy and molecular modeling, revealing structural insights into these isomeric dipeptides.

Recommended citation: Patrick Batoon, Yuntao Zhang, Giel Berden, Jos Oomens, Jianhua Ren. (2019). "Characterization of protonated AcAlaDab and AcDabAla by IRMPD spectroscopy and molecular modeling." International Journal of Mass Spectrometry, 444, 116178. https://doi.org/10.1016/j.ijms.2019.116178
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Synthesis and Mass Spectrometry Analysis of Oligo-peptoids

Published in Journal of Visualized Experiments, (132):56652, 2018, 2018

This article presents a method for manual synthesis of oligo-peptoids and sequence analysis using tandem mass spectrometry (MS/MS) techniques.

Recommended citation: Jianhua Ren, Yadwinder S Mann, Yuntao Zhang, Michael D Browne. (2018). "Synthesis and Mass Spectrometry Analysis of Oligo-peptoids." J Vis Exp, (132):56652. https://doi.org/10.3791/56652
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