CV

Yuntao Zhang

yuntao.zhang@bms.com
https://yuntaozhang999.github.io
, San Francisco Bay Area, US
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Summary

Senior scientist at Bristol Myers Squibb.

Education

  • Bioanalytical and Physical Chemistry
    2021-05
    University of the Pacific
  • Environmental Engineering
    2014-05
    University of the Pacific
  • Ecology
    2012-06
    University of Science and Technology Beijing

Work Experience

  • Scientist – Senior Scientist
    Oct. 2021 - Present
    Bristol Myers Squibb
    Redwood City / San Francisco Bay Area, CA
    • Leading mass spectrometry characterization and high-resolution Carbene Footprinting for epitope/paratope mapping to support biologics, ADCs, and cell therapy pipelines.
    • Co-inventor of anti-LRRC15 antibodies and antibody-drug conjugates (ADCs) (granted US patent / WIPO international patent applications).
    • Spearheaded deep learning workflows and foundation model fine-tuning (e.g. ST-Tahoe single-cell perturbation) and automated LC-MS data analysis pipelines.
    • Mentored data science and bioinformatics interns (Recipient of the CABS Mentor Impact Award).
  • Research Assistant & Lab Instructor
    Aug. 2016 - Aug. 2021
    University of the Pacific
    Stockton, CA
    • Investigated structural and energetic properties of peptoids/peptides using advanced MS and computational modeling.
    • Developed computational workflows for peptide/peptoid characterization; contributed to peer-reviewed publications.
    • Mentored 25+ undergraduate and graduate students in peptide synthesis, mass spectrometry, and molecular modeling.

Publications

  • Anti-LRRC15 Antibody Drug Conjugates
    2026
    World Intellectual Property Organization (WIPO) & USPTO
    Sayumi Yamazoe, Sonia G. Tanlimco, Lore Florin, Philip M. Vitorino, Qinqin Cheng, Christine H. Tan, Yuntao Zhang, Sunitha Bachawal, Hok Yee Chan, Winse Hong Morishige, Andrew W. Drake, Deanne M. Lathers, Jaimee C. Wong. (2026). "Anti-LRRC15 Antibody Drug Conjugates." WIPO Patent Publication No. WO/2026/112472 A1 (U.S. Patent Application No. US 2026/0144884 A1; U.S. Notice of Allowance Issued).
    View Publication
  • Anti-LRRC15 Antibodies and Uses Thereof
    2026
    World Intellectual Property Organization (WIPO) & USPTO
    Bristol-Myers Squibb Company (Co-inventor: Yuntao Zhang). (2026). "Anti-LRRC15 Antibodies and Uses Thereof." WIPO Patent Publication No. WO/2026/112469 A1 (U.S. Patent Application No. US 2026/0144885 A1).
    View Publication
  • Chirality effects on the intrinsic acidity of isomeric tripeptides containing a D/L-Cysteine on the N-terminus: CAA and dCAA
    2025
    International Journal of Mass Spectrometry
    Wang, S., Buen, Z., Harvey, K. R., Zhang, Y., & Ren, J. (2025). International Journal of Mass Spectrometry, 514, 117472. Volume 514, August 2025, 117472. Department of Chemistry, University of the Pacific, 3601 Pacific Avenue, Stockton, CA, 95211, USA. Received 9 March 2025, Revised 17 May 2025, Accepted 18 May 2025, Available online 20 May 2025, Version of Record 27 May 2025.
    View Publication
  • Subtle chirality effects of a D/l-Cysteine on the intrinsic acidity and conformation of isomeric tripeptides ACA and AdCA
    2021
    International Journal of Mass Spectrometry
    Zhang, Y., Buen, Z., Browne, M. D., Mann, Y. S., & Ren, J. (2021). International Journal of Mass Spectrometry, 469, 116685. Volume 469, November 2021, 116685. Department of Chemistry, University of the Pacific, 3601 Pacific Avenue, Stockton, CA, 95211, USA. Received 20 May 2021, Revised 11 August 2021, Accepted 17 August 2021, Available online 24 August 2021, Version of Record 26 August 2021.
    View Publication
  • Mass spectrometry studies of the fragmentation patterns and mechanisms of protonated peptoids
    2020
    Biopolymers
    Ren, J., Tian, Y., Hossain, E., Ho, J. S., Mann, Y. S., Zhang, Y., ... & Zuckermann, R. N. (2020). Biopolymers, 111(7), e23358.
    View Publication
  • Characterization of protonated AcAlaDab and AcDabAla by IRMPD spectroscopy and molecular modeling
    2019
    International Journal of Mass Spectrometry
    Batoon, P., Zhang, Y., Berden, G., Oomens, J., & Ren, J. (2019). International Journal of Mass Spectrometry, 444, 116178.
    View Publication
  • Synthesis and mass spectrometry analysis of oligo-peptoids
    2018
    JoVE (Journal of Visualized Experiments)
    Ren, J., Mann, Y. S., Zhang, Y., & Browne, M. D. (2018). JoVE (Journal of Visualized Experiments), (132), e56652.
    View Publication

Presentations

  • Chirality Induced Conformational and Thermochemical Changes in Cysteine Polyalanine Peptides
    2020
    Conference on Ion Chemistry and Mass Spectrometry, UCLA
    Los Angeles, CA, USA
    Oral Presentation. Authors: Yuntao Zhang, Joshua S. Ho, Jianhua Ren.
  • How Can D-Amino Acids Influence the Conformations and the Acidities of Oligopeptides?
    2019
    Conference on Ion Chemistry and Mass Spectrometry, UCLA
    Los Angeles, CA, USA
    Oral Presentation. Authors: Yuntao Zhang, Joshua Ho, Jianhua Ren.
  • Revealing the Remarkable Basicity and the Fine Structures of Lysine-Alanine Dipeptides by IRMPD and Computational Studies
    2021
    69th ASMS, Philadelphia
    Philadelphia, PA, USA
    Poster Presentation. Authors: Yuntao Zhang, Patrick Batoon, Shiyuan Wang, Giel Berden, Jos Oomens, Jianhua Ren.
  • Systematic Alteration of Gas-Phase Acidities and Conformations with Insertion of a D-Amino Acid in Oligopeptides
    2019
    67th ASMS, Atlanta
    Atlanta, GA, USA
    Poster Presentation. Authors: Yuntao Zhang, Joshua S. Ho, Jianhua Ren.
  • Conformations and Energetics of B- and Y-Ions in Peptoid Fragmentation
    2019
    67th ASMS, Atlanta
    Atlanta, GA, USA
    Poster Presentation. Authors: Joshua S. Ho, Yuntao Zhang, Jianhua Ren.
  • Understanding the Perplexing and Interesting Pathways of Peptoid Fragmentation
    2019
    67th ASMS, Atlanta
    Atlanta, GA, USA
    Poster Presentation. Authors: Yadwinder S. Mann, Yuntao Zhang, Jianhua Ren.
  • Chirality Induced Gas-Phase Acidity and Conformational Changes in Cysteine-Polyalanine Peptides
    2018
    66th ASMS, San Diego
    San Diego, CA, USA
    Poster Presentation. Authors: Yuntao Zhang, Jianhua Ren.
  • Gas-Phase Acidities and Conformations of Oligopeptide Epimers with D- and L-Cysteine
    2017
    65th ASMS, Indianapolis
    Indianapolis, IN, USA
    Poster Presentation. Authors: Yuntao Zhang, Zachary Buen, Jianhua Ren.

Teaching

  • General Chemistry (CHEM23) Lab
    University of the Pacific, Chemistry Department
    Role: Undergraduate course
    This course is designed for general interest in physical science and for preparation for further study in chemistry.
  • General Chemistry (CHEM25) Lab
    University of the Pacific, Chemistry Department
    Role: Undergraduate course
    The important general principles, theories and concepts of chemistry are studied, including fundamentals of chemistry and equilibrium.
  • General Chemistry (CHEM27) Lab
    University of the Pacific, Chemistry Department
    Role: Undergraduate course
    More important general principles, theories, and concepts of chemistry are studied including modern applications of quantum mechanics, bonding, chemical kinetics, liquids, solids, properties of solutions, coordination compounds, organic chemistry and biochemistry.
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